- Hematological Normal Values of Koreans
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Sang In Kim, Han Ik Cho
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Korean J Cytopathol. 1970;4(1):17-22.
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- Hematological normal values of 1103 Koreans including number of RBC, hemoglobin, hematocrit, reticulocyte, number of WBC. Differential counts of WBC, were studied. Mean values according to age and sex were obtained. Results are as table II.
- Adenocanthoma of the Stomach (A Case Report)
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Moon Ho Yang, Hyo Sook Park, Je G. Chi, Sang In Kim
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Korean J Cytopathol. 1969;3(2):59-63.
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- Adenoacanthoma of the stomach is a rare lesion of obscure origin. Approximately 43 anthenticated cases of primary adenoacanthoma of the stomach have been compiled since the first description made by Rolleston and Trevor in 1905. No special clinical features could be found which help to separate this unusual cell type from the usual adenocarcinoma.
Three theories concerning the origin of these unusual tumors are 1) squamous cell metaplasia. 2)heterotopic islands of squamous cells, and 3) tumor cells arising from the direct stimulation of undifferentiated multipotential cells in gastric mucosa.
A 37-year-old Korean male was admitted to Seoul National university Hospital because of rapid weight loss, vomiting and epigastric fullness of 3 months duration. Physical examination revealed a 47kg. weighing male, but showing essentially negative in that no abdominal masses were palpable, no lymphadenopathy was noted, and rectal examination was normal. The significant laboratory data included an upper gastrointestinal series which demonstrated an large filling defect in pyloric antrum along the greater curvature, and findings of pyloric stenosis.
The resected stomach contained a polypoid, focally ulcerating neoplastic mass measuring 4 cm. in maximum cross, which is infiltrating deep into muscularis. Serosa is partly involved grossly by neoplastic tissue, and several swollen lymph nudes were encountered along the greater curvature. Microscopic examination revealed infiltrating tumor masses that are comprised partly by differentiated, focally pearl forming squamous cell nests invading into external muscularis. In areas there are atypical glandular component, with evidence of mucin production.
- Congenital Cystic Lung -An Autopsy Case Report of a Congenital cystic Lung associated with Hydramnios-
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Geung Hwan Ahn, Yong II Kim, Sang In Kim, Sang Kook Lee, Hae Sook Yun, Jung Eun Mok
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Korean J Cytopathol. 1969;3(1):21-25.
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- A case of congenital cystic disease of middle and lower lobe of right lung in premature female infant delivered at 8 months of gestation is reported.
The congenital cystic disease is relatively rare malformation.
Hydramnios and anasarca in the newborn infant were present and the cysts were lined by bronchial epithelium.
These clinicopathological findings are compatible with that of the case reported by Ch’in and Tang in 1949.
Embryologically the condition is of the nature of a malformation which starts when lung anlage had already undergone lobulation but cartilage, arteries, mucous glands and alveoli are not yet differentiated.
- Statistical and Hematological Studies on Leukemia among Koreans
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Han Ik Cho, Sang In Kim
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Korean J Cytopathol. 1968;2(2):115-124.
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- Three hundred and thirty seven 337cases of leukemia among Koreans, which are confirmed by hematological examination at the Department of Clinical Pathology, Seoul National at University Hospital from Jan.1957 to Oct.1968, were studied.
The results are as followings :
1. The number of leukemia patients seems to be increasing in recent years.
2. The sex ratio of male to female is 2.0:1.0. (Table 2).
3. The age distribution of leukemia cases indicates a relatively high incidence in young age groups (0-9 yrs ; 22%, 10-19 yrs: 20.0%) and low incidence in older age groups (50-59 yrs ; 7.2%, 60 &over 2.8%).
4. Type incidences of leukemias are ; 32.5% in Acute Myelocytic Leukemia, 28.1% in Acute Lymphocytic Leukemia 21.9% in Chronic Myelocytic Leukemia in decreasing order of frequency. The Chronic Lymphocytic Leukemia is only 0.6% of total leukemia cases. 5. The mean hemoglobin levels of the leukemia cases are less than 9 gm/dl. in 74% of total cases and more than 12 gm/dl. in 4.9%. Acute Leukemia cases reveal more severe anemia.
6. The total leukocyte counts are between 10.000 to 50.000/mm³ in 35.0% and less than 5, 000/mm³ in 13.0% of total leukemia cases respectively, and more than 100. 000/mm³ in 63% of the Chronic Myelocytic Leukemia cases.
7. Blast forms in initial peripneral blood differential count are less than 10 % in 11.8 % of the total acute myelocytic leukemia cases and 22.0% Acute Lymhocytic Leukemis respectively.
8. The mean values of initial bone marrow differential counts reveal 61.2% of Myeloblasts and promyelocytes in acute myelocytic leukemia, 63.8 % of lymphoblasts and immature lymphocytes in Acute Lymphocytic Leukemia and 57.7 % of stab and segmented neutrophils in Chronic Myelocytic Leukemia respectively.
9. Basophils are increased in Chronic Myelocytic Leukemia, (3.0% in bone marrow, 5. 1% in peripheral blood).
- A Histopathologic Study on Lung Carcinoma
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Sang In Kim, Chong Soo Lee, Je G. Chi
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Korean J Cytopathol. 1967;1(1):17-22.
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- A Study was made on 104 cases (autopsy and biopsy) of primary lung carcinoma of Koreans obtained during a period of 10 years, 1957 to 1966, at the Department of Pathology, College of Medicine, Seoul National University.
The frequency ratio or relative incidence of lung cancer among all types of malignant tumors in the same period at this Department was 4.7 per cent in male and female together, thus ranking the sixth in frequency in male and the sixteenth in female.
The sex ratio of male and female was 5.5:1. The age distribution of lung cancer showed the highest frequency in the decade of 50-59 (34%) and also considerably high frequencies in the decades of 40-49 (27%) and 60-69 (26%). However, when related to the female only, 60-69 group was in the highest frequency. Ages of 104 cases ranged from 26 years to 79 years with the average of 48.2 years of age.
The one hundred and four cases of lung carcinoma were classified histologically into five types : squamous cell carcinoma 45 cases (43%), adenocarcinoma 29 cases (28%), oat cell carcinoma 17 cases (16%), undifferentiated carcinoma 12 cases (12%) and mixed type 1 case (0.9%).
It was emphasized that several findings of this study are in concord with the results of several other countries that are in definitely increasing tendency of lung cancer.
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